7-aminonicotinic acid
5-Bromo-2-chloro-3-fluoropyridine
CAS: 831203-13-5
Molecular Formula: C5H2BrClFN
7-aminonicotinic acid - Names and Identifiers
7-aminonicotinic acid - Physico-chemical Properties
| Molecular Formula | C5H2BrClFN |
| Molar Mass | 210.43 |
| Density | 1.829±0.06 g/cm3(Predicted) |
| Melting Point | 50-52℃ |
| Boling Point | 195.3±35.0 °C(Predicted) |
| Flash Point | 71.9°C |
| Vapor Presure | 0.592mmHg at 25°C |
| Appearance | Solid |
| Color | White |
| pKa | -2.44±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.555 |
| MDL | MFCD03411574 |
7-aminonicotinic acid - Risk and Safety
| Risk Codes | R22 - Harmful if swallowed R37/38 - Irritating to respiratory system and skin. R41 - Risk of serious damage to eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection. |
| Hazard Class | IRRITANT |
7-aminonicotinic acid - Reference Information
| Introduction | 2-chloro-3-fluoro-5-bromopyridine is a white or off-white solid at normal temperature and pressure, in the industry can be used as pesticides, dyeing AIDS, and synthesis of a series of products (including drugs, disinfectants, dyes, etc.). |
| Use | 2-chloro-3-fluoro-5-bromopyridine can be used as a medicine, disinfectant, dyes and pesticides in the synthesis of raw materials, in organic synthesis conversion, due to the nature of the lack of electrons in pyridine, combined with bromine atoms and chlorine atoms itself easy to leave the nature, the bromine unit and the chlorine unit in 2-chloro-3-fluoro-5-bromopyridine can be attacked by a nucleophilic reagent to undergo an aromatic nucleophilic substitution reaction. |
| preparation method | 5-bromo-3-fluoro-2-hydroxypyridine (10.0g) the suspension in phosphorus oxychloride (50 mL) was heated at 150°C for 4 hours, the mixture was poured into ice, the pH of the resulting mixture was adjusted to 10 by adding potassium carbonate and extracted with dichloromethane, the organic extract was dried over anhydrous magnesium sulfate, filtered, and then concentrated in vacuo to give the desired product. Fig.2-synthesis of chloro-3-fluoro-5-bromopyridine |
Last Update：2024-04-09 20:52:54
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Product Name: 5-Bromo-2-Chloro-3-Fluoropyridine Visit Supplier Webpage Request for quotation
CAS: 831203-13-5
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Mobile: 18021002903
QQ: 3008007409
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CAS: 831203-13-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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